| NCT03940742 |
A Study of Tirzepatide in Participants With Impaired Liver Function |
https://ClinicalTrials.gov/show/NCT03940742 |
Recruiting |
Eli Lilly and Company |
2020-08-18 |
| NCT03341884 |
A Study of Ipatasertib in Participants With Mild, Moderate or Severe Hepatic Impairment Compared to Healthy Participants |
https://ClinicalTrials.gov/show/NCT03341884 |
Completed |
Genentech, Inc. |
2018-06-26 |
| NCT03312036 |
HEpatic Regeneration With COupled Plasma Filtration and Adsorption for Liver Extracorporeal Detoxification |
https://ClinicalTrials.gov/show/NCT03312036 |
Completed |
St. Orsola Hospital |
2018-12-21 |
| NCT03306667 |
Clinical Pharmacology of FYU-981 (Subjects With Hepatic Insufficiency) |
https://ClinicalTrials.gov/show/NCT03306667 |
Completed |
Mochida Pharmaceutical Company, Ltd. |
2018-06-20 |
| NCT03172884 |
Study of Copanlisib in Hepatic or Renal Impairment |
https://ClinicalTrials.gov/show/NCT03172884 |
Completed |
Bayer |
2020-03-13 |
| NCT03082885 |
The Efficacy and Safety of Thymosin-α1 in Patients With HBV-related ACLF |
https://ClinicalTrials.gov/show/NCT03082885 |
Completed |
Sun Yat-sen University |
2019-06-02 |
| NCT02946554 |
Phase II Safety Study of 2 Dose Regimens of HepaStem in Patients With ACLF |
https://ClinicalTrials.gov/show/NCT02946554 |
Active, not recruiting |
Promethera Biosciences |
2019-07-31 |
| NCT02894385 |
Effect of Hepatic and Renal Impairment on the Pharmacokinetics, Safety and Tolerability of BAY1841788 (ODM-201) |
https://ClinicalTrials.gov/show/NCT02894385 |
Completed |
Bayer |
2017-04-10 |
| NCT02837939 |
Transfer Factor Efficacy in the Management of Cirrhosis-associated Immune Dysfunction |
https://ClinicalTrials.gov/show/NCT02837939 |
Recruiting |
Pavol Jozef Safarik University |
2020-07-31 |
| NCT02753517 |
Hepato Biliary Scintigraphy to Assess the Risk of Postoperative Liver Failure Hepatectomies |
https://ClinicalTrials.gov/show/NCT02753517 |
Recruiting |
University Hospital, Lille |
2020-11-30 |
| NCT02719210 |
High Volume Plasma Exchange in Children With Acute Liver Failure and Acute on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT02719210 |
Completed |
Institute of Liver and Biliary Sciences, India |
2018-11-30 |
| NCT02718079 |
High-Volume Plasma Exchange Versus Standard Medical Treatment in Patients With Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT02718079 |
Completed |
Institute of Liver and Biliary Sciences, India |
2018-10-08 |
| NCT02691533 |
To Study the Immunomodulating Effects and Safety Profile of ω3 and ω6 PUFA Containing Intravenous Lipid Emulsion in Patients With Acute on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT02691533 |
Completed |
Institute of Liver and Biliary Sciences, India |
2017-12-31 |
| NCT02689245 |
Randomized Controlled Trial Comparing the Efficacy and Safety of FMT in Hepatitis B Reactivation Leads to Acute on Chronic Liver Failure. |
https://ClinicalTrials.gov/show/NCT02689245 |
Completed |
Institute of Liver and Biliary Sciences, India |
2018-03-13 |
| NCT02669680 |
Granulocyte Colony Stimulating Factor (G-CSF) to Treat Acute-on-chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT02669680 |
Active, not recruiting |
University of Leipzig |
2020-03-31 |
| NCT02666352 |
A Study of the Pharmacokinetics of Uprifosbuvir (MK-3682) and Ruzasvir (MK-8408) in Participants With Moderate and Severe Hepatic Insufficiency (MK-3682-029) |
https://ClinicalTrials.gov/show/NCT02666352 |
Completed |
Merck Sharp & Dohme Corp. |
2017-01-16 |
| NCT02583698 |
Efficacy of Nonselective Beta Blocker vs Placebo in Patients With Acute-on-chronic Liver Failure With Small/ no Esophageal Varices |
https://ClinicalTrials.gov/show/NCT02583698 |
Completed |
Institute of Liver and Biliary Sciences, India |
2017-07-01 |
| NCT03065699 |
Safety and Performance Trial of DIALIVE Liver Dialysis Device in Acute On Chronic Liver Failure Patients |
https://ClinicalTrials.gov/show/NCT03065699 |
Active, not recruiting |
Yaqrit Ltd |
2019-12-31 |
| NCT02573727 |
To Compare the Response Rate of Noradrenaline vs. Terlipressin in Hepatorenal Syndrome in Patients With Acute on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT02573727 |
Completed |
Institute of Liver and Biliary Sciences, India |
2017-01-31 |
| NCT02786836 |
13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALF |
https://ClinicalTrials.gov/show/NCT02786836 |
Completed |
University of Texas Southwestern Medical Center |
2019-09-18 |
| NCT02467348 |
Incidence And Outcome Of Paracentesis Induced Circulatory Dysfunction In Acute-On-Chronic Liver Failure. |
https://ClinicalTrials.gov/show/NCT02467348 |
Completed |
Institute of Liver and Biliary Sciences, India |
2017-01-31 |
| NCT02457702 |
Mitochondrial Function in Patients With Severe Liver Disease |
https://ClinicalTrials.gov/show/NCT02457702 |
Recruiting |
University of Texas Southwestern Medical Center |
2021-12-31 |
| NCT02390713 |
Pneumatic Reversible Portal Vein Diameter Modulation After Major Hepatectomy |
https://ClinicalTrials.gov/show/NCT02390713 |
Recruiting |
Assistance Publique - Hôpitaux de Paris |
2020-04-30 |
| NCT02387814 |
A Study of Abemaciclib in Participants With Varying Degrees of Liver Impairment |
https://ClinicalTrials.gov/show/NCT02387814 |
Completed |
Eli Lilly and Company |
2015-08-31 |
| NCT02375867 |
Steroids in Fulminant Hepatitis A in the Pediatric Age Group |
https://ClinicalTrials.gov/show/NCT02375867 |
Completed |
National Liver Institute, Egypt |
2017-08-31 |
| NCT02334800 |
A Study To Describe The Effect Of Impaired Hepatic Function Of The Pharmacokinetics Of Palbociclib |
https://ClinicalTrials.gov/show/NCT02334800 |
Completed |
Pfizer |
2016-10-09 |
| NCT02321371 |
Effect of Goal Directed Ammonia Lowering Therapy in Acute on Chronic Liver Failure Patients With Hepatic Encephalopathy. |
https://ClinicalTrials.gov/show/NCT02321371 |
Completed |
Institute of Liver and Biliary Sciences, India |
2016-01-31 |
| NCT02310542 |
Comparison of Two Liver Dialysis Systems : MARS Versus SPAD in Severe Liver Failure |
https://ClinicalTrials.gov/show/NCT02310542 |
Completed |
Hospices Civils de Lyon |
2017-09-30 |
| NCT02265627 |
Pharmacokinetics, Safety and Tolerability of BIIL 284 BS in Patients With Hepatic Impairment in Comparison to Healthy Volunteers |
https://ClinicalTrials.gov/show/NCT02265627 |
Completed |
Boehringer Ingelheim |
2000-09-30 |
| NCT02259855 |
Pharmacokinetics (PK) of Tipranavir/Ritonavir, Ribavirin, Pegylated Interferon (Peg INF) in Hepatitis C (HCV) Subjects With Mild Hepatic Impairment and in HCV, Hepatitis B (HBV), Hepatitis D Infected Subjects or Alcoholic Cirrhosis With Moderate Hepatic Impairment |
https://ClinicalTrials.gov/show/NCT02259855 |
Completed |
Boehringer Ingelheim |
2008-10-31 |
| NCT02249442 |
Study to Determine the Pharmacokinetics on TPV/r in Subjects With Mild and Moderate Hepatic Insufficiency |
https://ClinicalTrials.gov/show/NCT02249442 |
Completed |
Boehringer Ingelheim |
2004-06-30 |
| NCT02184091 |
Study to Evaluate the Effects of Underlying Renal or Hepatic Dysfunction on the Pharmacokinetics of Nevirapine |
https://ClinicalTrials.gov/show/NCT02184091 |
Completed |
Boehringer Ingelheim |
1999-07-31 |
| NCT02170571 |
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Dabigatran Etexilate in Patients With Moderate Hepatic Impairment Compared to Subjects With Normal Hepatic Function |
https://ClinicalTrials.gov/show/NCT02170571 |
Completed |
Boehringer Ingelheim |
2005-12-31 |
| NCT02161224 |
A Study to Investigate the Exposure and Safety and Tolerability of a Single Dose of FG-4592 in Subjects With Moderately Diminished Liver Function Compared to Those With Normal Liver Function |
https://ClinicalTrials.gov/show/NCT02161224 |
Completed |
Astellas Pharma Inc |
2013-12-31 |
| NCT02120547 |
Phase 1 Study of Multiple-Dose Pharmacokinetics of Cenicriviroc in Subjects With Mild and Moderate Hepatic Impairment |
https://ClinicalTrials.gov/show/NCT02120547 |
Completed |
Tobira Therapeutics, Inc. |
2014-07-31 |
| NCT02115321 |
Study of Efficacy and Safety of Grazoprevir (MK-5172) + Elbasvir (MK-8742) in Chronic Hepatitis C Participants With Child-Pugh (CP)-B Hepatic Insufficiency (MK-5172-059) |
https://ClinicalTrials.gov/show/NCT02115321 |
Completed |
Merck Sharp & Dohme Corp. |
2015-03-05 |
| NCT02090621 |
Extracorporeal Photopheresis After Liver Transplant |
https://ClinicalTrials.gov/show/NCT02090621 |
Completed |
Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia |
2013-10-31 |
| NCT02089659 |
A Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Doravirine (MK-1439) (MK-1439-019) |
https://ClinicalTrials.gov/show/NCT02089659 |
Completed |
Merck Sharp & Dohme Corp. |
2014-05-12 |
| NCT01273493 |
A Pharmacokinetic Study of Trabectedin in Patients With Advanced Malignancies and Hepatic Dysfunction |
https://ClinicalTrials.gov/show/NCT01273493 |
Completed |
Janssen Research & Development, LLC |
2014-04-30 |
| NCT01946360 |
Role of 13C Methacetin Breath Test in Predicting Prognosis Among Patients With Acute or Acute on Chronic Liver Failure (ACLF). |
https://ClinicalTrials.gov/show/NCT01946360 |
Completed |
Institute of Liver and Biliary Sciences, India |
2015-01-31 |
| NCT01916993 |
Safety, Tolerability, and Pharmacokinetics of a Single Dose of NBI-98854 in Subjects With Mild,Moderate, or Severe Hepatic Insufficiency |
https://ClinicalTrials.gov/show/NCT01916993 |
Completed |
Neurocrine Biosciences |
2013-12-31 |
| NCT01870388 |
A Pharmacokinetic Study of Baricitinib in Participants With Liver Disease |
https://ClinicalTrials.gov/show/NCT01870388 |
Completed |
Eli Lilly and Company |
2013-07-31 |
| NCT01860326 |
Evaluate the Pharmacokinetics, Safety, and Tolerability of Alisporivir in Subjects With Hepatic Impairment Compared to Healthy Subjects |
https://ClinicalTrials.gov/show/NCT01860326 |
Completed |
Debiopharm International SA |
2011-09-30 |
| NCT01846455 |
Single Dose Pharmacokinetics of Suboxone Study in Hepatic Impaired Subjects |
https://ClinicalTrials.gov/show/NCT01846455 |
Completed |
Indivior Inc. |
2013-04-30 |
| NCT01836185 |
A Study of Evacetrapib (LY2484595) in Participants With Hepatic (Liver) Impairment |
https://ClinicalTrials.gov/show/NCT01836185 |
Completed |
Eli Lilly and Company |
2013-10-31 |
| NCT01797536 |
The Influence of Hepatic Insufficiency on the Pharmacokinetics of Elbasvir (MK-8742) (MK-8742-009) |
https://ClinicalTrials.gov/show/NCT01797536 |
Completed |
Merck Sharp & Dohme Corp. |
2014-08-20 |
| NCT01751399 |
A Single Dose Study of LY2605541 in Participants With Liver Impairment |
https://ClinicalTrials.gov/show/NCT01751399 |
Completed |
Eli Lilly and Company |
2013-09-30 |
| NCT01737684 |
A Single-Dose Study of the Pharmacokinetics of Vibegron (MK-4618) in Adults With Hepatic Insufficiency (MK-4618-013) |
https://ClinicalTrials.gov/show/NCT01737684 |
Completed |
Merck Sharp & Dohme Corp. |
2013-06-14 |
| NCT01643447 |
Ulinastatin Preventing Postoperative Hepatic Failure in Hepatocellular Carcinoma (HCC) |
https://ClinicalTrials.gov/show/NCT01643447 |
Completed |
Eastern Hepatobiliary Surgery Hospital |
2014-12-31 |
| NCT01634230 |
Emergency Use of OCR-002 in Acute Liver Failure (ALF) |
https://ClinicalTrials.gov/show/NCT01634230 |
Completed |
Mallinckrodt |
2013-05-31 |
| NCT01548690 |
Safety Study of Ornithine Phenylacetate to Treat Patients With Acute Liver Failure/Severe Acute Liver Injury |
https://ClinicalTrials.gov/show/NCT01548690 |
Completed |
University of Texas Southwestern Medical Center |
2017-02-23 |
| NCT01512693 |
Assessment of Pharmacokinetics of Single Dose Odanacatib (MK-0822) in Participants With Moderate Hepatic Insufficiency (MK-0822-070) |
https://ClinicalTrials.gov/show/NCT01512693 |
Completed |
Merck Sharp & Dohme Corp. |
2012-04-24 |
| NCT01475136 |
A Study of LY2140023 in Hepatic Impaired Participants |
https://ClinicalTrials.gov/show/NCT01475136 |
Completed |
Eli Lilly and Company |
2012-12-31 |
| NCT01394497 |
Use of N-Acetylcysteine During Liver Procurement |
https://ClinicalTrials.gov/show/NCT01394497 |
Completed |
Azienda Ospedaliera di Padova |
2009-07-31 |
| NCT01390428 |
Study to Investigate the Influence of Hepatic Insufficiency on the Pharmacokinetics of Grazoprevir (MK-5172-013) |
https://ClinicalTrials.gov/show/NCT01390428 |
Completed |
Merck Sharp & Dohme Corp. |
2014-09-05 |
| NCT01383460 |
Efficacy of Granulocyte Colony-stimulating Factor and Erythropoetin for Patients With Acute-on-chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT01383460 |
Completed |
Institute of Liver and Biliary Sciences, India |
2013-01-31 |
| NCT04243655 |
Use of HA 330-II for Hemofiltration in Patients With ALF as a Bridge to Liver Transplantation . |
https://ClinicalTrials.gov/show/NCT04243655 |
Recruiting |
Asian Institute of Gastroenterology, India |
2020-10-31 |
| NCT04238416 |
Intravenous Branched Chain Amino Acids for Hepatic Encephalopathy in ACLF |
https://ClinicalTrials.gov/show/NCT04238416 |
Recruiting |
Postgraduate Institute of Medical Education and Research |
2022-09-30 |
| NCT04160039 |
Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit |
https://ClinicalTrials.gov/show/NCT04160039 |
Recruiting |
Medical College of Wisconsin |
2020-12-31 |
| NCT04157465 |
Anti-fungal Strategies in Acute-on-Chronic Liver Failure Patients |
https://ClinicalTrials.gov/show/NCT04157465 |
Recruiting |
Postgraduate Institute of Medical Education and Research |
2020-12-31 |
| NCT04147936 |
Study of the Safety and Tolerability of AXA1665 in Subjects With Mild and Moderate Hepatic Insufficiency |
https://ClinicalTrials.gov/show/NCT04147936 |
Recruiting |
Axcella Health, Inc |
2020-03-31 |
| NCT04089969 |
Cardiac Risk Assessment Using Standard of Care Versus CTA and Heart Flow FFRct |
https://ClinicalTrials.gov/show/NCT04089969 |
Recruiting |
William Beaumont Hospitals |
2022-11-01 |
| NCT04013113 |
Efficacy and Safety of Hemoperfusion or Plasma Exchange Compared to Standard Medical Therapy in Patients With Acute on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT04013113 |
Recruiting |
Institute of Liver and Biliary Sciences, India |
2020-07-31 |
| NCT03987893 |
PEG3350 in ACLF With Hepatic Encephalopathy |
https://ClinicalTrials.gov/show/NCT03987893 |
Recruiting |
Postgraduate Institute of Medical Education and Research |
2020-05-25 |
| NCT03920618 |
Three Types of Nucleotide/Nucleoside Analogues Treatment in HBV Related ACLF |
https://ClinicalTrials.gov/show/NCT03920618 |
Recruiting |
Third Affiliated Hospital, Sun Yat-Sen University |
2023-10-31 |
| NCT03882346 |
Study to Evaluate Safety and Efficacy of LifeLiver in Acute or Acute-on-Chronic Liver Failure Patients |
https://ClinicalTrials.gov/show/NCT03882346 |
Recruiting |
HLB Cell Co., Ltd. |
2022-03-31 |
| NCT03860155 |
Allogeneic ABCB5-positive Stem Cells for Treatment of Acute-on-Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT03860155 |
Recruiting |
RHEACELL GmbH & Co. KG |
2021-10-31 |
| NCT03842761 |
A Study to Test How Different Doses of BI 685509 Are Tolerated in Patients With Liver Problems |
https://ClinicalTrials.gov/show/NCT03842761 |
Recruiting |
Boehringer Ingelheim |
2021-05-21 |
| NCT03791190 |
RCA for CRRT in Liver Failure and High Risk Bleeding Patients |
https://ClinicalTrials.gov/show/NCT03791190 |
Recruiting |
Fourth Military Medical University |
2021-08-30 |
| NCT03754400 |
Efficacy of Albumin Therapy With Standard Medical Treatment (SMT) as Compared to Standard Medical Treatment (SMT) in Improving Patient Survival and Immune Modulation in Patients With Acute on Chronic Liver Failure (ASIA Trial). |
https://ClinicalTrials.gov/show/NCT03754400 |
Recruiting |
Institute of Liver and Biliary Sciences, India |
2020-07-30 |
| NCT03737448 |
TRimetazidine for acUte on Chronic Liver Failure STudy |
https://ClinicalTrials.gov/show/NCT03737448 |
Recruiting |
Martin Pharmaceuticals |
2020-02-28 |
| NCT03713489 |
Platelet Transfusion in HBV-related acute-on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT03713489 |
Recruiting |
Nanfang Hospital of Southern Medical University |
2019-09-30 |
| NCT03702920 |
Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5% |
https://ClinicalTrials.gov/show/NCT03702920 |
Recruiting |
Grifols Therapeutics LLC |
2021-12-31 |
| NCT03668171 |
Mesenchymal Stem Cell Transplantation for Acute-on-chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT03668171 |
Recruiting |
Xijing Hospital of Digestive Diseases |
2019-12-31 |
| NCT03667157 |
Liver Function After Intravenous Methylprednisolone Administration |
https://ClinicalTrials.gov/show/NCT03667157 |
Completed |
Medical University of Warsaw |
2016-10-30 |
| NCT03589820 |
Plasma Exchange and Continuous Hemodiafiltration in Treatment of Wilson’s Disease-related Liver Failure |
https://ClinicalTrials.gov/show/NCT03589820 |
Enrolling by invitation |
Third Affiliated Hospital, Sun Yat-Sen University |
2020-06-28 |
| NCT03577938 |
Study on the Optimal Strategy for Acute-on-chronic Liver Failure With Integrative Treatment |
https://ClinicalTrials.gov/show/NCT03577938 |
Recruiting |
Beijing 302 Hospital |
2020-12-30 |
| NCT03576859 |
Pyrophosphate Homeostasis and Hepatic Expression of ABCC6.Pyro-TH |
https://ClinicalTrials.gov/show/NCT03576859 |
Recruiting |
Centre Hospitalier Universitaire de Nice |
2020-11-06 |
| NCT03515980 |
An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function |
https://ClinicalTrials.gov/show/NCT03515980 |
Completed |
Bristol-Myers Squibb |
2019-08-29 |
| NCT03465059 |
Safety and Pharmacokinetics of Zanubrutinib (BGB-3111) in Healthy Subjects and Those With Impaired Liver Function |
https://ClinicalTrials.gov/show/NCT03465059 |
Completed |
BeiGene |
2018-10-19 |
| NCT01261923 |
Pharmacokinetics of 9-cis-retinoic Acid (Alitretinoin, Toctino®) in Patients With Hepatic Disease |
https://ClinicalTrials.gov/show/NCT01261923 |
Completed |
University Hospital, Gentofte, Copenhagen |
2011-08-31 |
| NCT01254994 |
The Efficacy and Safety of Entecavir Treatment of Patients With Acute on Chronic Hepatitis B Liver Failure |
https://ClinicalTrials.gov/show/NCT01254994 |
Completed |
Sun Yat-sen University |
2009-07-31 |
| NCT01186588 |
A Study of Canagliflozin in Study Participants With Various Degrees of Impaired Hepatic (Liver) Function |
https://ClinicalTrials.gov/show/NCT01186588 |
Completed |
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. |
2011-04-30 |
| NCT01114490 |
Pharmacokinetics of Anacetrapib (MK0859) in Patients With Hepatic Insufficiency (MK-0859-039) |
https://ClinicalTrials.gov/show/NCT01114490 |
Completed |
Merck Sharp & Dohme Corp. |
2010-07-31 |
| NCT01111318 |
Pharmacokinetics of Empagliflozin (BI 10773) in Patients With Impaired Liver Function |
https://ClinicalTrials.gov/show/NCT01111318 |
Completed |
Boehringer Ingelheim |
2010-11-30 |
| NCT01074645 |
Randomized Controlled Trial of Tenofovir in Patients of Reactivation of Hepatitis B Presenting as Acute on Chronic Liver Failure |
https://ClinicalTrials.gov/show/NCT01074645 |
Completed |
Govind Ballabh Pant Hospital |
2009-06-30 |
| NCT01043926 |
Pharmacokinetics of Suvorexant in Participants With Hepatic Insufficiency (MK-4305-017) |
https://ClinicalTrials.gov/show/NCT01043926 |
Completed |
Merck Sharp & Dohme Corp. |
2010-04-14 |
| NCT01043887 |
Ridaforolimus in Patients With Hepatic Insufficiency (MK-8669-046) |
https://ClinicalTrials.gov/show/NCT01043887 |
Completed |
Merck Sharp & Dohme Corp. |
2010-04-30 |
| NCT01019070 |
Hepatic Impaired Subjects Compared to Healthy Subjects Receiving Multi-dose BMS-650032 |
https://ClinicalTrials.gov/show/NCT01019070 |
Completed |
Bristol-Myers Squibb |
2011-08-31 |
| NCT01010906 |
A Study Investigating the Influence of Hepatic Insufficiency on the Pharmacokinetics of Vaniprevir (MK-7009-005) |
https://ClinicalTrials.gov/show/NCT01010906 |
Completed |
Merck Sharp & Dohme Corp. |
2010-06-11 |
| NCT00969813 |
A Safety and Tolerability Study of CP-690,550 in Subjects With Hepatic Impairment and Normal Hepatic Function |
https://ClinicalTrials.gov/show/NCT00969813 |
Completed |
Pfizer |
2010-01-31 |
| NCT00968591 |
Pharmacokinetics of Everolimus in Subjects With Hepatic Insufficiency |
https://ClinicalTrials.gov/show/NCT00968591 |
Completed |
Novartis |
2010-11-30 |
| NCT00950508 |
A Study of the Effect of Plasmaexchange in Patients With Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT00950508 |
Completed |
Rigshospitalet, Denmark |
2009-07-31 |
| NCT00931060 |
Effects of Branched-Chain Amino Acids on Muscle Ammonia Metabolism in Patients With Cirrhosis and Healthy Subjects |
https://ClinicalTrials.gov/show/NCT00931060 |
Completed |
University of Aarhus |
2009-06-30 |
| NCT00859053 |
Single-Dose Pharmacokinetics of BMS-790052 in Participants With Hepatic Impairment |
https://ClinicalTrials.gov/show/NCT00859053 |
Completed |
Bristol-Myers Squibb |
2009-09-30 |
| NCT04221672 |
The Effect of Terlipressin on Recovery of Liver Function After Hepatectomy |
https://ClinicalTrials.gov/show/NCT04221672 |
Recruiting |
Shanghai Zhongshan Hospital |
2020-12-30 |
| NCT02910739 |
An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016) |
https://ClinicalTrials.gov/show/NCT02910739 |
Completed |
Merck Sharp & Dohme Corp. |
2017-04-03 |
| NCT00831532 |
Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [Pf-01913539] In Subjects With Hepatic Impairment And Normal Hepatic Function |
https://ClinicalTrials.gov/show/NCT00831532 |
Completed |
Pfizer |
2009-08-31 |
| NCT02191865 |
Nintedanib in Volunteers With Hepatic Impairment Compared With Healthy Volunteers |
https://ClinicalTrials.gov/show/NCT02191865 |
Completed |
Boehringer Ingelheim |
2014-12-31 |
| NCT00805090 |
Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects |
https://ClinicalTrials.gov/show/NCT00805090 |
Completed |
Javelin Pharmaceuticals |
2009-03-31 |
| NCT03011424 |
Early Postoperative Extracorporal Liver Support Therapy (ELS) as a Tool to Manage Post Hepatectomy Liver Failure (PLF) |
https://ClinicalTrials.gov/show/NCT03011424 |
Completed |
Karolinska University Hospital |
2015-05-31 |
| NCT02183376 |
Pharmacokinetics and Pharmacodynamics of BI 1356 in Subjects With Different Degrees of Liver Impairment as Compared to Healthy Subjects |
https://ClinicalTrials.gov/show/NCT02183376 |
Completed |
Boehringer Ingelheim |
2009-03-31 |
| NCT03968848 |
Investigate the Influence of Severe Hepatic Impairment on the Pharmacokinetics of Acalabrutinib and Its Metabolite |
https://ClinicalTrials.gov/show/NCT03968848 |
Completed |
Acerta Pharma BV |
2019-03-13 |
| NCT03773887 |
Comparison of Inflammatory Profiles and Regenerative Potential in Alcoholic Liver Disease |
https://ClinicalTrials.gov/show/NCT03773887 |
Recruiting |
University Hospital, Lille |
2020-12-31 |
| NCT00781430 |
Study Evaluating The PK And Safety Of Neratinib In Healthy Subjects And Subjects With Chronic Liver Disease |
https://ClinicalTrials.gov/show/NCT00781430 |
Completed |
Puma Biotechnology, Inc. |
2010-02-28 |
| NCT00764049 |
Single Pass Albumin Dialysis in Patients With Cirrhosis |
https://ClinicalTrials.gov/show/NCT00764049 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2012-01-31 |
| NCT00696826 |
A Study of MK0431 in Patients WIth Hepatic Insufficiency (0431-017)(COMPLETED) |
https://ClinicalTrials.gov/show/NCT00696826 |
Completed |
Merck Sharp & Dohme Corp. |
2004-05-31 |
| NCT00692341 |
Evaluation Of Hepatic Impairment On AG-013736 Pharmacokinetics |
https://ClinicalTrials.gov/show/NCT00692341 |
Completed |
Pfizer |
2008-10-31 |
| NCT00670124 |
Hypothermia to Prevent High Intracranial Pressure in Patients With Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT00670124 |
Completed |
Rigshospitalet, Denmark |
2011-01-31 |
| NCT00655707 |
A Phase I/II Safety and Tolerability Dose Escalation Study of Autologous Stem Cells to Patients With Liver Insufficiency |
https://ClinicalTrials.gov/show/NCT00655707 |
Completed |
Imperial College London |
2009-04-30 |
| NCT00655304 |
The Effect of Prometheus (R) Liver Support Dialysis on Cerebral Metabolism in Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT00655304 |
Completed |
Rigshospitalet, Denmark |
2010-12-31 |
| NCT00645021 |
Study Examining The Effect Of Hepatic Impairment On Safety, Toleration And How The Body Processes An Experimental Drug |
https://ClinicalTrials.gov/show/NCT00645021 |
Completed |
Pfizer |
2008-10-31 |
| NCT00614146 |
Recompensation of Exacerbated Liver Insufficiency With Hyperbilirubinemia and/or Encephalopathy and/or Renal Failure |
https://ClinicalTrials.gov/show/NCT00614146 |
Completed |
Baxter Healthcare Corporation |
2008-01-31 |
| NCT01201720 |
Effects on Plasma Exchange on Functional Capacity of Serum Albumin, Circulatory Dysfunction, Renal and Cerebral Function in Cirrhotic Patients With “Acute-on-chronic Liver Failure” |
https://ClinicalTrials.gov/show/NCT01201720 |
Completed |
Grifols Therapeutics LLC |
2013-01-31 |
| NCT00522730 |
Safety and Tolerance on Lipids of Parenteral and Enteral Nutrition in Critically Ill Patients With Liver Failure |
https://ClinicalTrials.gov/show/NCT00522730 |
Completed |
Cliniques universitaires Saint-Luc- Université Catholique de Louvain |
2009-08-31 |
| NCT00509210 |
Study of Telaprevir in Subjects With Hepatic Impairment |
https://ClinicalTrials.gov/show/NCT00509210 |
Completed |
Vertex Pharmaceuticals Incorporated |
2008-06-30 |
| NCT00416702 |
Safety and Pharmacokinetics of Indacaterol in Healthy Subjects and Those With Impaired Liver Function |
https://ClinicalTrials.gov/show/NCT00416702 |
Completed |
Novartis |
NA |
| NCT00407004 |
Elimination of Albumin-Bound Substances by MARS and Prometheus |
https://ClinicalTrials.gov/show/NCT00407004 |
Completed |
Medical University of Graz |
NA |
| NCT00314054 |
Study Evaluating the Safety of HCV-796 in Subjects With Liver Disease and in Healthy Adults |
https://ClinicalTrials.gov/show/NCT00314054 |
Completed |
Wyeth is now a wholly owned subsidiary of Pfizer |
2007-10-31 |
| NCT00248625 |
N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT00248625 |
Completed |
University of Pittsburgh |
2009-09-30 |
| NCT00224705 |
The MARS® Albumin Dialysis System in Patients With Fulminant and Subfulminant Hepatic Failure |
https://ClinicalTrials.gov/show/NCT00224705 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2009-01-31 |
| NCT00162552 |
Clinical Trial of Pentoxifylline in Patient With Cirrhosis |
https://ClinicalTrials.gov/show/NCT00162552 |
Completed |
Assistance Publique - Hôpitaux de Paris |
2007-12-31 |
| NCT00147043 |
Adult Stem Cell Therapy in Liver Insufficiency |
https://ClinicalTrials.gov/show/NCT00147043 |
Completed |
Imperial College London |
2005-06-30 |
| NCT00144248 |
A Pharmacokinetic Study to Assess Nevirapine [Viramune] Levels in HIV Infected Patients With Impaired Hepatic Functions |
https://ClinicalTrials.gov/show/NCT00144248 |
Completed |
Boehringer Ingelheim |
2006-06-30 |
| NCT00030225 |
Phase 2 Evaluation of the ELAD System in the Management of Acute Liver Failure |
https://ClinicalTrials.gov/show/NCT00030225 |
Completed |
Vital Therapies, Inc. |
2003-02-28 |
| NCT00004467 |
Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen |
https://ClinicalTrials.gov/show/NCT00004467 |
Completed |
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
2006-11-30 |